Connor Holly

Project

Comprehensive Health Testing Guide

A longevity-focused guide to health testing by sex, age, and health status

Why This Exists

Most people don't know what blood tests to get beyond whatever their doctor orders once a year. The standard annual physical misses the markers that actually predict disease decades early: ApoB, fasting insulin, Lp(a), homocysteine.

I wanted a single reference that covers what to test, when to test it, what the optimal ranges are (not just "normal"), and which providers to use. Something I could share with friends and family who ask "what tests should I get?"

Used Claude Opus 4.5 and GPT 5.2x-high to synthesize research from longevity medicine, then organized it by sex, age, and actionability. The 80/20 at the top covers what everyone should do; the rest goes deeper.

Not medical advice. These are longevity-focused targets which may be more aggressive than standard clinical guidelines.

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What's Inside

  • 80/20 Quick Start:5 tests that catch 80% of issues for $600-750
  • 🧬Whole Genome Sequencing:Provider comparison, data ownership, what to look for
  • ❤️Cardiovascular:ApoB, Lp(a), homocysteine, CAC score
  • 🧪Metabolic:Fasting insulin, HbA1c, glucose
  • 👨Male-Specific:Testosterone, free T, SHBG, PSA
  • 👩Female-Specific:Cycle mapping, DUTCH test, thyroid, iron
  • 🎯Target Ranges:Color-coded green/yellow/red for each marker
  • 🏥Provider Deep Dive:Pros/cons of each, discount lab brokers, my current thinking
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Read the Guide

The full guide is a standalone interactive document with filtering by age and sex. This is a living document that I update as I learn more.

Open Full Guide ↗
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Disclaimer: This guide is for educational purposes only. It reflects longevity-focused targets which may be more aggressive than standard clinical guidelines. Always consult qualified healthcare providers before making health decisions.